Unearthing Nature's Medicines

Lodo Therapeutics Corporation is a drug discovery and development company focused on the creation of novel therapeutics derived from nature that will impact patients around the world. Lodo seeks to work in partnership with global pharmaceutical companies and world leading non-governmental organizations (NGO's) to tackle some of the greatest challenges in human health: drug-resistant microbial infections and cancers.

Lodo Therapeutics was created to pursue the scientific vision of Dr. Sean Brady at Rockefeller University and co-founded by Dr. David Pompliano (Ex. Merck, Revolution Medicine). Lodo Therapeutics identifies and produces bioactive natural products directly from the microbial DNA sequence information contained in soil. Lodo believes that the potential cures for a number of deadly and/or debilitating diseases literally lie at our feet. Information encoded in bacterial genomes, not experimental serendipity, drives our discovery of new medicines. Not constrained by traditional culture-based approaches to natural products drug discovery, Lodo Therapeutics has unlocked a vast trove of overlooked compounds evolutionarily selected for processes essential for life.

Lodo Therapeutics, an Accelerator Life Science Partners-backed entity, is headquartered in New York City. The company's lab and offices are located in the Alexandria Center for Life Science, New York City's first and only premier life science park.

Our Backers

Our Partners

Our Team

The initial management of Lodo Therapeutics will be provided by Accelerator Life Science Partners' core management team of talented professionals with deep investment, operational and scientific expertise. For more information visit: Accelerator — Senior Leadership


Steve Colletti, Ph.D.

Senior Vice President, R&D

Brad Hover, Ph.D.

Director of Research

Sean Brady, Ph.D.

Academic Advisor


Our Board


Barbara Dalton, Ph.D.

Pfizer Ventures

Johnston Erwin

Eli Lilly and Company

Steve Gillis, Ph.D.

ARCH Venture Partners

Sundar Kodiyalam


Thong Le

Accelerator Life Science Partners

Joel S. Marcus, J.D., C.P.A.

Alexandria Real Estate Equities, Inc.

Asish Xavier, Ph.D.


Career Opportunities

Join the Team

We're looking for good people

Current Openings

Please check back for future opportunities.

Please send your resume to:
Lodo Therapeutics Corporation
Attn: Human Resources
430 E 29th St, Suite 625
New York, NY 10016


Press Releases

May 9, 2018 Lodo Therapeutics Corporation Forms Multi-Target Strategic Collaboration with Genentech [link]
January 18, 2016 Accelerator Corporation Launches Lodo Theraepeutics with $17 Million Series A to Develop Therapies Derived From Natural Products [link]

In The News

What if the best pharmacy on the planet is waiting to be discovered in the soils beneath our feet? [www.tedmed.com]
December 28, 2018 Nature Reviews Drug Discovery volume 18, pages 1011 (2019) [www.nature.com]
May 9, 2018 Genentech forms $1B discovery collaboration with soil-prospector Lodo Therapeutics [www.fiercebiotech.com]
May 9, 2018 Genentech, Lodo Therapeutics Ink Up-to-$969M Metagenomics Drug Discovery Partnership [www.genengnews.com]
February 12, 2018 Scientists Unearth Hope for New Antibiotics [www.wsj.com]
February 12, 2018 Powerful Antibiotics Found in Dirt [www.directorsblog.nih.gov]
February 12, 2018 A potentially powerful new antibiotic is discovered in dirt [www.washingtonpost.com]
February 12, 2018 New antibiotic family discovered in dirt [www.bbc.com]
February 12, 2018 New type of antibiotic discovered in soil in breakthrough for fight against drug-resistant superbugs [www.theindependent.co.uk]
February 12, 2018 In soil-dwelling bacteria, scientists find a new weapon to fight drug-resistant superbugs [www.latimes.com]
January 18, 2018 How Dirt Could Save Humanity From an Infectious Apocalypse [www.wired.com]
April 11, 2017 Nature Biotechnology's academic spinouts of 2016 [www.nature.com]
October 31, 2016 C&EN's 10 Start-ups to watch [www.cen.ACS.org]
January 18, 2016 Lodo loads up series A with $17m [www.globaluniversityventuring.com]
January 18, 2016 Lodo Therapeutics completes venture financing [www.biocentury.com]
January 12, 2016 Accelerator debuts Lodo [www.biocentury.com]
January 11, 2016 Accelerator, Gates Team Up in NY to Put $17M Into Rockefeller Startup [www.xconomy.com]
January 11, 2016 Accelerator's second NYC biotech startup sets out with $17M and Gates-backed science [www.fiercebiotech.com]
January 11, 2016 New York gets Biotech Boost [www.cen.acs.org]
January 11, 2016 Nice slice of 'mud' pie as Accelerator launches Lodo with $17M series A [www.bioworld.com]
January 11, 2016 Gates-backed NYC startup plumbs soil bacteria for tuberculosis therapy [www.medcitynews.com]
January 11, 2016 Life science investment group Accelerator Corp. backs two New York startups [www.geekwire.com]
January 11, 2016 Seattle-based Accelerator Corp. launches first New York companies with $65M in funding [www.bizjournals.com]
January 11, 2016 Daily funding roundup [www.vator.tv]